Week 1 action lands at SoFi Stadium as the Los Angeles Chargers host the Arizona Cardinals on Mon, 14 Sept, at 6:25 am AEST. Both squads are eager to build momentum early in the campaign after dropping their recent starts, setting up a fascinating battle in Los Angeles.

Who Takes the Win at SoFi Stadium?

The numbers say the Chargers enter as the head-to-head favourites at 1.17, with the visiting Cardinals currently unseated at 5.1. Los Angeles holds a 1-2 overall record with 62 points scored and 68 points against, leaving them with a -6 point differential. They are coming off a tight 18–20 loss against the Los Angeles Rams on Fri, 28 Aug, which followed a 17–41 defeat against the San Francisco 49ers on Fri, 21 Aug, leaving them 0-2 at home.

Arizona arrives at SoFi Stadium with a 1-3 overall record, accumulating 108 points for and 123 against (-15 differential). In their most recent start on Sat, 29 Aug, the Cardinals dropped a high-scoring 38–42 contest away to the Green Bay Packers after a 13–34 loss to the Dallas Cowboys on Sun, 23 Aug. For punters scanning our latest nfl picks, Arizona's 1-1 road split shows they can score away from home. While Los Angeles holds the edge on paper, Arizona's scoring output keeps this contest very interesting.

Head to HeadOdds correct as at 8:30 am AEST. Odds can change.
Solid tickOur tip: Los Angeles Chargers. Los Angeles holds the home-ground advantage and enters as head-to-head favourites against an Arizona defense that has surrendered 123 points overall.

Tipped at $1.17 (1:21 pm AEST). Opinion, not a guarantee. Gamble responsibly — 18+.

Head-to-head context

Season and last-five scoring — context for the match-winner market.

20.7Season avg points for27
22.7Season avg points against30.8
33%Season win rate25%
17.5Last 2 avg points for25.5
0%Last-five win rate0%

Covering the Line Spread

The line is set at 10.5 points, with Los Angeles Chargers -10.5 offered at 2.0 and Arizona Cardinals +10.5 available at 1.8. That gives Arizona a double-digit start on the road.

Big tick for Arizona's attack away from home, having pushed Green Bay to a four-point margin (38–42) in their last outing. Los Angeles dropped their last start by just 2 points (18–20) to the Rams, but lost by 24 points to the 49ers in their previous home match. Getting +10.5 points jumps off the page for the visitors to keep this contest within reach.

LineOdds correct as at 6:12 am AEST. Odds can change.
Solid tickOur tip: Arizona Cardinals +10.5. Arizona put up 38 points on the road in their last start and rates a real chance to cover a double-digit start.

Tipped at $1.80 (1:21 pm AEST). Opinion, not a guarantee. Gamble responsibly — 18+.

Line cover (form)

Cover rate applies this match's live spread to recent completed scores — not a season ATS record.

Los Angeles Chargers-9.5last 2

Cover rate0%0/2
Avg margin (-13)avg -13vs 9.5
-1714

Arizona Cardinals+9.5last 2

Cover rate50%1/2
0%Cover % (form)50%

Same Game Multi Combo Options

Multiple priced combinations are available for punters building a multi. A Chargers victory combined with touchdown scorers Omarion Hampton and Ladd McConkey is sitting at 3.4.

For those looking at an Arizona victory, a multi pairing Cardinals to win with Jeremiyah Love and Tyler Allgeier to score a touchdown is quoted at 15.